Poison centre notification in Italy
Verified against ECHA’s member state overview ·
Italy receives harmonised notifications from the ECHA Submission portal into the Archivio Preparati Pericolosi (APP) at the Istituto Superiore di Sanità, accepts dossiers in Italian or English, and is one of the six member states where the product may only be placed on the market after the submission report confirms receipt by the appointed body.
Italy's fee is a flat one: €50 per registrant per year, paid to ISS, whatever the number of mixtures you register that year, and not subject to VAT or stamp duty. For a company notifying dozens of mixtures that's one payment; for a company notifying one, it's the same €50.
Like Germany, Italy extends notification beyond the EU baseline: all detergents are notifiable in Italy even when they are not classified as hazardous, a national rule that predates and survives Annex VIII harmonisation.
What to watch for in Italy
- Confirmation of receipt required before placing on the Italian market.
- Fee: €50 per registrant per year to ISS. Checked on 15 October 2026.
- National extra: all detergents notifiable regardless of classification.
The submission itself is the same in every member state that accepts the ECHA route: a PCN dossier in ECHA’s current format, with the mixture’s UFI, its full composition and its product category. See how to submit a PCN for the process end to end, or compare the 30 countries in the country overview table.
Frequently asked questions
What does PCN registration cost in Italy?
€50 per registrant per year, paid to the Istituto Superiore di Sanità. The fee is annual and per company, so registering one or one hundred mixtures in a year costs the same, and it's not subject to VAT or stamp duty.
Do non-hazardous detergents need notification in Italy?
Yes. Italy requires all detergents to be notified even if not classified as hazardous. That's a national rule on top of the harmonised Annex VIII duty, which by itself only covers hazardous mixtures.
When can I start selling in Italy after submitting a PCN?
Only after the ECHA submission report confirms the dossier has been received by ISS. Italy requires confirmation of receipt, so passed validation alone doesn't open the market.
Sources
- Overview of Member States decisions (MSD), ECHA, v14, May 2026.
- Appointed bodies list, ECHA, accessed July 2026.
- Istruzioni per la notifica, Istituto Superiore di Sanità (ISS), checked 15 October 2026.